TNFSF13B - TNF superfamily member 13b Gene

Also Known as DTL; BAFF; BLYS; CD257; TALL1; THANK; ZTNF4; TALL-1; TNLG7A; TNFSF20

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 10673

About TNFSF13B

Cytogenetic location: 13q33.3 Genomic coordinates (GRCh38): 13:108,269,629-108,308,484 (from NCBI)

This gene has 6 transcripts (splice variants), 224 orthologues and 2 paralogues. Broad expression in appendix (RPKM 11.4), lymph node (RPKM 7.1) and 21 other tissues.

Summary

The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptors TNFRSF13B/TACI, TNFRSF17/BCMA, and TNFRSF13C/BAFFR. This cytokine is expressed in B cell lineage cells, and acts as a potent B cell activator. It has been also shown to play an important role in the proliferation and differentiation of B cells. Alternatively spliced transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Mar 2011]

TNFSF13B Products (2)

mRNA Protein Name
NM_001145645.2 NP_001139117.1 tumor necrosis factor ligand superfamily member 13B isoform 2
NM_006573.5 NP_006564.1 tumor necrosis factor ligand superfamily member 13B isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
10801128 GOA
Biological Process GO Annotation Evidence References Source
involved in positive regulation of B cell proliferation IMP
IMP: Inferred from mutant phenotype
17499850 GOA
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
19828625 GOA
located in perinuclear region of cytoplasm IDA
IDA: Inferred from direct assay
19828625 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

TNFSF13B Protein Structure

TNF

TNF: TNF(Tumour Necrosis Factor) family (172 - 284)

  • 0
  • 100
  • 200
  • 285 a.a.
Protein Preferred Names Protein Names

tumor necrosis factor ligand superfamily member 13B

  • ApoL related ligand TALL-1

TNFSF13B Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
TNFSF13B Q9Y275 CSE1L Homo sapiens P55060
Pull Down
30833792
Intra
TNFSF13B Q9Y275 KPNB1 Homo sapiens Q14974
Pull Down
30833792
Intra
TNFSF13B Q9Y275 TNFRSF13B Homo sapiens O14836
FACS
10956646
Intra
TNFSF13B Q9Y275 TNFRSF13B Homo sapiens O14836
SPR
10956646
Cross: Cross-species interaction Intra: Intraspecies interaction

Recombinant TNFSF13B Proteins

Cat. No. Product Name Accession Purity
HY-P7003 BAFF/TNFSF13B Protein, Human (CHO) Q9Y275-1 (A134-L285) ≥ 95%, as determined by reducing SDS-PAGE.
HY-P70428 BAFF/TNFSF13B Protein, Human (HEK293, His) Q9Y275-1 (A134-L285) ≥ 95%, as determined by reducing SDS-PAGE.
HY-P70730 BAFF/TNFSF13B Protein, Human (HEK293, Fc) Q9Y275-1 (A134-L285) ≥ 95%, as determined by reducing SDS-PAGE.
HY-P78384 BAFF/TNFSF13B Trimer Protein, Human (HEK293, His-Flag) Q9Y275-1 (T141-L285) ≥ 95%, as determined by Bis-Tris PAGE.
HY-P78385 BAFF/TNFSF13B Protein, Human (HEK293, Fc-Flag) Q9Y275-1 (T141-L285) ≥ 95%, as determined by Bis-Tris PAGE.
HY-P700017AF Animal-Free BAFF/TNFSF13B Protein, Human (His) Q9Y275-1 (A134-L285) ≥ 95%, as determined by reducing SDS-PAGE.
HY-P700459 BAFF/TNFSF13B Protein, Human (Biotinylated, HEK293, hFc-Avi) Q9Y275-1 (A134-L285) ≥ 90%, as determined by reducing SDS-PAGE.
HY-P700531 BAFF/TNFSF13B Protein, Human (His-SUMO) Q9Y275-1 (Q68-L285) ≥ 90%, as determined by reducing SDS-PAGE.

TNFSF13B Antibodies

Cat. No. Product Name Application Reactivity
HY-P81765 BAFF Antibody (YA1510) FC, ELISA Human
HY-P84885 BAFF Antibody (YA4582) WB, ICC/IF, FC, ELISA Human
HY-P84885A BAFF Antibody (YA4582)(PBS only) WB, ICC/IF, FC, ELISA Human

Related Diseases

Diseases Alias
Sjogren Syndrome

  • Sicca Syndrome

  • Sjogren'S Syndrome

  • Sjögren Syndrome

  • Sjogren-Gougerot Syndrome

  • Keratoconjunctivitis Sicca

  • Sjögren'S Syndrome

  • Xerodermosteosis

  • Dacryosialoadenopathia Atrophicans

  • Gougerot-Houwer-Sjogren Syndrome

  • Gougerot-Sjogren Syndrome

  • Keratoconjunctivitis Sicca-Xerostomia

  • Secreto-Inhibitor-Xerodermostenosis

  • Primary Sjogren Syndrome

  • Primary Sjogren-Gougerot Syndrome

  • Sjogrens Syndrome Primary

  • Sjogrens Syndrome

  • Dry Eye Syndromes
Autoimmune Disease

  • Autoimmune Diseases

  • Autoimmune Hypersensitivity Disease

  • Hypersensitivity Reaction Type Ii Disease

  • Type Ii Hypersensitivity Reaction Disease
Cryoglobulinemia

  • Cryoimmunoglobulinaemia
Vasculitis

  • Angiitis

  • Autoimmune Vasculitis

  • Systemic Vasculitis

  • Vasculitis, Autoimmune
Common Variable Immunodeficiency

  • Cvid

  • Common Variable Agammaglobulinemia

  • Common Variable Immune Deficiency

  • Acquired Hypogammaglobulinemia

  • Hypogamma-Globulinemia, Acquired

  • Idiopathic Immunoglobulin Deficiency

  • Primary Antibody Deficiency

  • Primary Hypogammaglobulinemia

  • Acquired Agammaglobulinemia

  • Sporadic Hypogammaglobulinemia

  • Common Variable Hypogamma-Globulinemia

  • Immunoglobulin Deficiency, Late-Onset

  • Common Variable Hypogammaglobulinemia

  • Immunodeficiency, Common Variable
Neuromyelitis Optica

  • Devic Disease

  • Devic Syndrome

  • Neuromyelitis Optica Spectrum Disorder

  • Devic'S Disease

  • Devic'S Syndrome

  • Devic'S Neuromyelitis Optica

  • Nmo

  • Nmo Spectrum Disorder

  • Neuromyelitis Optica Spectrum Disorders

  • Devic Neuromyelitis Optica

  • Optic-Spinal Ms

  • Opticospinal Ms

  • Nmosd

  • Opticospinal Multiple Sclerosis

  • Devic

  • Ophthalmoneuromyelitis

  • Optic Neuromyelitis

  • Optic Neuroencephalomyelopathy

  • Nmo - [Neuromyelitis Optica]

  • Optic Neuritis With Demyelination
Macroglobulinemia

  • Primary Macroglobulinemia

  • Waldenstrom Macroglobulinemia
Myasthenia Gravis

  • MG

  • Acquired Myasthenia

  • Autoimmune Myasthenia Gravis

  • Erb-Goldflam Disease

  • Mg - [Myasthenia Gravis]

  • Myasthenia Gravis Nos

  • Myasthenia
Pemphigus Foliaceus

  • Pemphigus Foliaceous

  • Pf

  • Superficial Pemphigus
Bullous Pemphigoid

  • Benign Pemphigus

  • Senile Dermatitis Herpetiformis

  • Old Age Pemphigus

  • Parapemphigus

  • Pemphigoid

  • Pemphigoid Bullous

  • Pemphigoid, Bullous
Mixed Connective Tissue Disease

  • Sharp Syndrome

  • Mctd

  • Connective Tissue Disease Overlap Syndrome

  • Mixed Collagen Vascular Disease

  • Mctd - [Mixed Connective Tissue Disease]
Purpura

  • Purpuric Disorder
Systemic Lupus Erythematosus

  • Lupus Nephritis

  • SLE

  • Disseminated Lupus Erythematosus

  • Systemic Lupus Erythematosus, Susceptibility To

  • Lupus Erythematosus, Systemic

  • Lupus Nephritis, Susceptibility To

  • Libman-Sacks Disease

  • Systemic Lupus Erythematosus Susceptibility To

  • Sle - Lupus Erythematosus, Systemic

  • Le Syndrome

  • Lupus

  • Lupus Erythematosus Systemic

  • Lupus Erythematosus, Systemic, Susceptibility To

  • Lupus Vulgaris

  • Lupus Erythematosus, Discoid

  • Lupus Erythematosus

  • Systemic Lupus Erythematosus Nos

  • Sle - [Systemic Lupus Erythematosus]
Pemphigus Vulgaris, Familial

  • Pemphigus Vulgaris

  • Familial Pemphigus Vulgaris

  • Pemphigus
Refractory Plasma Cell Neoplasm
B-Cell Lymphoma

  • Lymphoma, B-Cell

  • B-Cell Lymphomas

  • B-Cell Lymphocytic Neoplasm

  • Lymphoma B-Cell

  • B-Cell Lymphoma Nos
Burkitt Lymphoma

  • Burkitt'S Lymphoma

  • BL

  • Burkitt Lymphoma, Somatic

  • Burkitt Lymphoma/Leukaemia

  • Burkitt'S Tumor

  • Burkitt'S Tumor Or Lymphoma

  • Malignant Lymphoma, Burkitt'S Type

  • Small Non-Cleaved Cell Lymphoma, Burkitt'S Type

  • Small Non-Cleaved Cell Lymphoma

  • Burkitt Tumor

  • Burkitts Lymphoma

  • Lymphoma, Small Noncleaved-Cell

  • Burkitt Tumour

  • Diffuse Small Noncleaved Malignant Burkitt Lymphoma

  • Malignant Burkitt Lymphoma

  • “Burkitt-Like” Lymphoma

  • Undifferentiated Burkitt Lymphoma

  • Small Noncleaved Cell Burkitt Lymphoma
Autoimmune Disease Of Exocrine System
Pemphigus
Rheumatoid Arthritis

  • RA

  • Arthritis, Rheumatoid

  • Rheumatoid Arthritis, Susceptibility To

  • Arthritis Or Polyarthritis, Rheumatic

  • Atrophic Arthritis

  • Rheumatism Arthritis

  • Rheumatoid Polyarthritis
Connective Tissue Disease

  • Connective Tissue Diseases

  • Connective Tissue Disorder

  • Abnormality Of Connective Tissue

  • Disorder Of Connective Tissue

  • Connective Tissue Disorders
Multiple Sclerosis

  • MS

  • Multiple Sclerosis, Susceptibility To

  • Disseminated Sclerosis

  • Multiple Sclerosis, Disease Progression, Modifier Of

  • Insular Sclerosis

  • Multiple Sclerosis Modifier Of Disease Progression

  • Multiple Sclerosis, Susceptibility To 1

  • Multiple Sclerosis, Susceptibility To, 1

  • Multiple Sclerosis 1

  • Generalized Multiple Sclerosis

  • Multiple Sclerosis Variant

  • Multiple Sclerosis Susceptibility To

  • Cerebrospinal Sclerosis

  • Generalised Multiple Sclerosis

  • Ms - [Multiple Sclerosis]

  • Disseminated Cerebrospinal Sclerosis

  • Disseminated Multiple Sclerosis

  • Disseminated Nervous System Myelosclerosis

  • Multiple Cerebrospinal Sclerosis

  • Multiple Combined Sclerosis

  • Multiple Sclerosis Generalised

  • Disseminated Brain Sclerosis

  • Disseminated Spinal Sclerosis

  • Insular Brain Sclerosis

  • Miliary Brain Sclerosis

  • Multiple Combined Sclerosis Of Spinal Cord

  • Multiple Ascending Sclerosis

  • Multiple Brain Sclerosis

  • Multiple Sclerosis Of Brain Stem

  • Multiple Sclerosis Of The Brain Stem

  • Multiple Sclerosis Of Cord

  • Sclérose En Plaques

  • Plaque Sclerosis

  • Multiple Sclerosis Of The Spinal Cord
Systemic Scleroderma

  • Scleroderma

  • Progressive Systemic Sclerosis

  • Systemic Sclerosis

  • Scleroderma, Systemic

  • Scleroderma Syndrome

  • Dermatosclerosis

  • Familial Progressive Scleroderma

  • Progressive Scleroderma

  • Scleroderma Disease

  • Scleroderma, Localized

  • Diffuse Scleroderma

  • Scleroderma, Familial Progressive
Potocki-Shaffer Syndrome

  • Proximal 11p Deletion Syndrome

  • Chromosome 11p11.2 Deletion Syndrome

  • Pss

  • 11p11.2 Deletion

  • P11pds

  • Defect11 Syndrome

  • Deletion Of Chromosome 11p11.2

  • POSHS
Lymphoid Interstitial Pneumonia

  • Lymphocytic Interstitial Pneumonia

  • Lip Disease

  • Lip Diseases

  • LIP

  • Disease Of Lips
Hyperglobulinemic Purpura

  • Purpura, Hyperglobulinemic
Immunodeficiency With Hyper-Igm, Type 4

  • HIGM4

  • Hyper-Igm Syndrome Type 4

  • Immunodeficiency With Hyper-Igm Type 4

  • Hyper-Igm Syndrome 4

  • Immunodeficiency With Hyper Igm Type 4

  • Hyper Igm Syndrome 4

  • Immunodeficiency, With Hyper Igm, Type 4
Temporal Arteritis

  • Polymyalgia Rheumatica

  • Giant Cell Arteritis

  • Cranial Arteritis

  • Horton Disease

  • Gca

  • Horton'S Disease

  • Rhizomelic Pseudopolyarthritis

  • Arteritis Cranialis

  • Arteritis Temporalis

  • Horton'S Arteritis

  • Horton'S Giant Cell Arteritis

  • Horton'S Temporal Arteritis

  • Horton'S Syndrome

  • Gca - [Giant Cell Arteritis]

  • Senile Arthritis

  • Polymyalgia Arteritica

  • Pmr - [Polymyalgia Rheumatica]

  • Forestier-Certonciny Syndrome

  • Rheumatic Polymyalgia

  • Polymyalgia
Lymphoma, Non-Hodgkin, Familial

  • Non-Hodgkin Lymphoma

  • Lymphoma, Non-Hodgkin

  • NHL

  • Lymphoma, Non-Hodgkin, Somatic

  • Lymphoma, Follicular, Somatic

  • Familial Non-Hodgkin Lymphoma

  • Lymphoma Non-Hodgkins

  • Follicular Lymphoma, Somatic

  • Lymphosarcoma

  • Non-Hodgkins Lymphoma
Autoimmune Disease Of Blood
B Cell Deficiency

  • Immunoglobulin Heavy Chain Deficiency

  • B Cell Deficiencies

  • Immunoglobulin Heavy Chain Deletion

  • Humoral Immune Defect
Xerophthalmia

  • Conjunctival Xerosis
Igg4-Related Disease

  • Multifocal Fibrosclerosis

  • Igg4-Related Sclerosing Disease

  • Igg4-Related Systemic Disease

  • Immunoglobulin G4-Related Sclerosing Disease

  • Hyper-Igg4 Disease

  • Igg4-Associated Disease

  • Igg4-Positive Multiorgan Lymphoproliferative Syndrome

  • Igg4-Related Autoimmune Disease

  • Igg4-Related Systemic Sclerosing Disease

  • Igg4-Syndrome

  • Multifocal Idiopathic Fibrosclerosis

  • Systemic Igg4-Related Plasmacytic Syndrome

  • Systemic Igg4-Related Sclerosing Syndrome

  • Mediastinal Fibrosis, Familial

  • Retroperitoneal Fibrosis, Familial

  • Igg4-Rd
Follicular Lymphoma

  • Lymphoma, Follicular

  • Lymphoma Follicular

  • Brill-Symmers' Disease

  • Large Cell Follicular Non-Hodgkin Lymphoma

  • Diffuse Follicle Centre Lymphoma

  • Diffuse Follicular Lymphoma Nos

  • Follicular Nodular Non-Hodgkin Lymphoma, Unspecified

  • Follicular Large Cell Cleaved Or Noncleaved Lymphoma

  • Large Cell Follicular Noncleaved Lymphoma

  • Follicular Lymphoma With Or Without Diffuse Areas

  • Histiocytic Follicular Lymphoma

  • Histiocytic Nodular Lymphoma

  • Histiocytic Nodular Malignant Lymphoma

  • Large Cell Follicular Lymphoma

  • Large Cell Noncleaved Follicular Lymphoma

  • Large Cell Noncleaved Follicular Malignant Lymphoma

  • Nodular Reticulum Cell Sarcoma

  • Noncleaved Follicular Lymphoma
Immune-Complex Glomerulonephritis

  • Immune Complex Glomerulonephritis
Dacryoadenitis

  • Dacryocystitis
Immunoglobulin Alpha Deficiency

  • Iga Deficiency

  • Gamma-A-Globulin Deficiency

  • Immunoglobulin A Deficiency
Sialadenitis

  • Sialoadenitis

  • Adenitis, Salivary Gland

  • Salivary Gland Inflammation

  • Salivary Gland Adenitis

  • Sialitis

  • Inflammation Of Salivary Gland

  • Inflammation Of Salivary Duct Or Gland

  • Salivary Glandular Adenitis

  • Sialoangiitis

  • Sialoangitis

  • Sialodochitis
Mikulicz Disease

  • Igg4-Related Dacryoadenitis And Sialadenitis

  • Mikulicz'S Disease

  • Chronic Dacryoadenitis And Sialadenitis

  • Mikulicz Syndrome

  • Mikulicz' Disease
Polyclonal Hypergammaglobulinemia

  • Polyclonal Gammopathy
Immunodeficiency With Hyper-Igm, Type 2

  • HIGM2

  • Hyper-Igm Syndrome Type 2

  • Hyper-Igm Syndrome 2

  • Immunodeficiency With Hyper-Igm Type 2

  • Activation-Induced Cytidine Deaminase Deficiency

  • Aid Deficiency

  • Immunodeficiency With Hyper Igm Type 2

  • Hyper Igm Syndrome 2

  • Immunodeficiency With Hyper-Igm 2

  • Hyper-Igm Immunodeficiency Type 2

  • Immunodeficiency, With Hyper Igm, Type 2

  • Hyper-Igm Immunodeficiency Syndrome, Type 2
Primary Thrombocytopenia
Malaria

  • Malaria, Susceptibility To

  • Malaria, Resistance To

  • Malaria, Cerebral

  • Cerebral Malaria

  • Malaria, Severe, Susceptibility To

  • Malaria, Severe, Resistance To

  • Malaria, Cerebral, Susceptibility To

  • Induced Malaria

  • Malaria, Vivax, Protection Against

  • Malaria, Severe

  • Malaria, Cerebral, Reduced Risk Of

  • Malaria, Protection Against

  • Resistance To Malaria Due To G6pd Deficiency

  • Malaria Due To G6pd Deficiency

  • Malarial Encephalitis

  • CM

  • Malaria Cerebral

  • Susceptibility To Malaria

  • Acute Pernicious Fever

  • Aestivo-Autumnal Fever

  • Aestivo Autumnal Malaria

  • Chagres Fever

  • Continued Malaria Fever

  • Estivo-Autumnal Fever

  • Estivo-Autumnal Malaria

  • Estivo-Autumnal Malarial Fever

  • Falciparum Fever

  • Malignant Tertian Fever

  • Malignant Tertian Malaria

  • Pernicious Intermittent Fever

  • Pernicious Malaria

  • Quotidian Malaria

  • Subtertian Fever

  • Subtertian Malaria Fever

  • Subtertian Malignant Tertian Malaria

  • Tropical Malaria

  • Algid Malaria

  • Bilious Haemoglobinuric Fever

  • Black Water Fever

  • Blackwater Fever

  • Malarial Blackwater Fever

  • Severe Malarial Falciparum

  • West African Fever

  • Malarial Haematinuria

  • Haemoglobinuric Fever

  • Haemoglobinuric Malaria

  • Severe Plasmodium Falciparum Malaria

  • Malarial Haemoglobinuria

  • Malarial Haematuria

  • Falciparum Malaria [Malignant Tertian]

  • Malaria Tropica

  • Malarial Shock

  • Chagres Virus Disease

  • Malignant Malaria

  • Mtm - [Malignant Tertian Malaria]

  • Tm -[Malignant Tertian Malaria]

  • Panama Fever

  • St - [Subtertian Malaria]

  • Malarial Quotidian

  • Benign Tertian Malaria

  • Tertian Ague

  • Vivax Fever

  • Plasmodium Vivax Malaria Nos

  • Btm - [Benign Tertian Malaria]

  • Bt - [Benign Tertian Malaria]

  • Vivax Malaria

  • Benign Tertian Vivax Malaria

  • Tertian Malaria

  • Quartan Malaria

  • Quartan Ague

  • Quartan Fever

  • Plasmodium Malariae Malaria Nos

  • Quartan Malarial

  • Malaria By Plasmodium Malariae

  • Malariae Malaria

  • Ovale Tertian Malaria

  • Plasmodium Ovale Fever

  • Malaria Fever By Plasmodium Ovale

  • Ovale Malaria

  • Malaria By Plasmodium Ovale

  • Malarial Ovale

  • Marsh Fever

  • Remittent Congestive Fever

  • Coastal Fever

  • Remittent Gastric Fever

  • Miasmatic Fever

  • Congestive Remittent Fever

  • Intermittent Fever

  • Jungle Fever

  • Paludism

  • Cameroon Fever

  • Ague

  • Corsican Fever

  • Intermittent Bilious Fever

  • Disease Due To Plasmodiidae

  • Malarial Fever

  • Plasmodiosis

  • Remittent Fever

  • Roman Fever

  • Malaria Fever Nos

  • Malaria Nos

  • Paludal Fever

  • Clinically Diagnosed Malaria

  • Clinically Diagnosed Malaria Without Parasitological Confirmation

  • Congestive Fever

  • Malarial Cachexia

  • Marsh Cachexia

  • Paludal Cachexia

  • Recurrent Malaria

  • Remittent Malaria
Autoimmune Disease Of Musculoskeletal System
Leukemia, Chronic Lymphocytic

  • Chronic Lymphocytic Leukemia

  • B-Cell Chronic Lymphocytic Leukemia

  • CLL

  • B-Cell Chronic Lymphoid Leukemia

  • Chronic Lymphatic Leukemia

  • Chronic Lymphocytic Leukaemia

  • Lymphoplasmacytic Leukemia

  • Small Lymphocytic Lymphoma

  • Leukemia, Chronic Lymphatic

  • B-Cell Chronic Lymphocytic Leukaemia

  • Chronic Lymphatic Leukaemia

  • Lymphoplasmacytic Leukaemia

  • B Cell Chronic Lymphocytic Leukemia

  • Chronic B-Cell Lymphocytic Leukemia

  • Leukemia, Lymphocytic, Chronic

  • B-Cll

  • Chronic Lymphoid Leukemia

  • Leukemia Lymphocytic Chronic

  • Lymphoma Small Lymphocytic

  • Leukemia, Lymphocytic, Chronic, B-Cell
Proliferative Glomerulonephritis
Progressive Multifocal Leukoencephalopathy

  • Pml

  • Leukoencephalopathy, Progressive Multifocal

  • Progressive Multifocal Leukoencephalitis

  • Leukoencephalopathy Progressive Multifocal

  • Pml - [Progressive Multifocal Leukoencephalopathy]
Keratoconjunctivitis Sicca

  • Kcs

  • Dry Eye Syndromes

  • Keratitis Sicca

  • Xerophthalmia
Cutaneous Lupus Erythematosus

  • Lupus Erythematosus, Cutaneous

  • Lupus Erythematosus Cutaneous
Thrombocytopenia Due To Platelet Alloimmunization

  • Immune Thrombocytopenia

  • Autoimmune Thrombocytopenia

  • Immune Thrombocytopenic Purpura

  • Itp

  • Auto-Immune Thrombocytopenia

  • Thrombocytopenia Due To Immune Destruction

  • Autoimmune Thrombocytopenic Purpura

  • Idiopathic Thrombocytopenic Purpura

  • Werlhof Disease
Heart Block, Congenital

  • Congenital Heart Block

  • Heart Block Congenital

  • Congenital Atrioventricular Block
Anemia, Autoimmune Hemolytic

  • Autoimmune Hemolytic Anemia

  • Idiopathic Autoimmune Hemolytic Anemia

  • Immuno-Hemolytic Anemia

  • Anemia, Hemolytic, Autoimmune

  • Autoimmune Haemolytic Anaemia

  • Autoimmune Hemolytic Anaemia

  • Acquired Autoimmune Hemolytic Anemia

  • Anemia Hemolytic Autoimmune

  • Familial Auto-Immune Hemolytic Anemia

  • Aha

  • Aiha
Immunodeficiency With Hyper-Igm, Type 1

  • Immunodeficiency, X-Linked, With Hyper-Igm

  • Hyper Igm Syndrome

  • HIGM1

  • Xhim

  • Hyper-Igm Syndrome

  • Higm

  • Hyper-Igm Syndrome 1

  • Immunodeficiency 3

  • Imd3

  • Immunodeficiency With Hyper-Igm

  • Immunodeficiency With Hyper Igm Type 1

  • Ihis

  • X-Linked Hyper Igm Syndrome

  • Hyper-Igm Immunodeficiency, X-Linked

  • Hyper Igm Immunodeficiency, X-Linked

  • Hyper Igm Syndrome 1

  • X-Linked Immunodeficiency With Hyper-Igm 1

  • Immunodeficiency, With Hyper Igm

  • Immunodeficiency, With Hyper Igm, Type 1

  • Hyper-Igm Immunodeficiency Syndrome, Type 1

  • Hyperimmunoglobulin M Syndrome
Thrombocytopenia

  • Low Platelet Count

  • Low Platelets

  • Decreased Platelets

  • Platelet Dysfunction Nos
Asymmetric Motor Neuropathy
Chromosomal Deletion Syndrome
Cerebritis
Autoimmune Disease Of Peripheral Nervous System
Central Nervous System Vasculitis

  • Vasculitis, Central Nervous System
Salivary Gland Disease

  • Salivary Gland Disorders

  • Salivary Gland Diseases

  • Non-Neoplastic Salivary Gland Disease

  • Non-Neoplastic Salivary Gland Disorder

  • Disorder Of Salivary Gland

  • Lesion Of Salivary Gland Nos
Hypersensitivity Reaction Type Iv Disease

  • Immunoproliferative Disorders

  • Immunoproliferative Disease
Asthma

  • Chronic Obstructive Asthma

  • Asthma, Diminished Response To Antileukotriene Treatment In

  • Bronchial Hyperreactivity

  • Asthma, Susceptibility To

  • Asthma, Bronchial

  • Asthma, Protection Against

  • Asthma, Nocturnal, Susceptibility To

  • Nocturnal Asthma

  • Asthma-Related Traits

  • Asthma-Related Traits, Susceptibility To

  • Asthma, Nocturnal

  • Chronic Obstructive Asthma With Acute Exacerbation

  • Chronic Obstructive Asthma With Status Asthmaticus

  • Exercise Induced Asthma

  • Exercise-Induced Asthma

  • Bronchial Asthma

  • Asthma, Exercise-Induced

  • Idiosyncratic Asthma

  • Unspecified Asthma With Acute Exacerbation

  • Asthma, Unspecified, With Stated Status Asthmaticus

  • Status Asthmaticus Nos

  • Acute Severe Asthma

  • Acute Severe Bronchial Asthma

  • Status Asthma

  • Status Post Asthmaticus
Immune Deficiency Disease

  • Immunodeficiency

  • Primary Immunodeficiency

  • Primary Immunodeficiency Disease

  • Immunologic Deficiency Syndromes

  • Hypoimmunity

  • Immune Deficiency Disorder

  • Immunodeficiency Syndrome

  • Immune Disorder

  • Primary Immune Deficiency Disorder

  • Immune System Diseases

  • Human Immunodeficiency Virus Infection

  • Hiv - [Human Immunodeficiency Virus Infection]

  • Hiv Positive Nos

  • Hiv Disease

  • Acquired Immune Deficiency Syndrome-Related Complex

  • Aids-Like Syndrome

  • Aids-Related Complex Nos

  • Arc - [Aids-Related Complex]

  • Immunodeficiency Due To Human Immunodeficiency Virus Infection

  • Unspecified Human Immunodeficiency Virus Disease

  • Hiv Disease Nos

  • Human Immunodeficiency Virus Positive Nos

  • Hiv Nos

  • Deficiency Of Complement Initial Pathway

  • Deficiency Of Complement Terminal Pathway

  • Cfdd - [Complement Factor D Deficiency]

  • Immunodeficiency With Nk-Cell - [Natural-Killer Cell] Deficiency

  • Nonfamilial Hypogammaglobulinaemia

  • Common Variable Immune Deficiency

  • Nonfamilial Agammaglobulinaemia

  • Common Variable Agammaglobulinaemia

  • Agammaglobulinaemia Nos

  • Agammaglobulinaemia Antibody Deficiency Syndrome

  • Hypogammaglobulinaemia Antibody Deficiency Syndrome

  • Acquired Agammaglobulinaemia Nos

  • Hypogammaglobulinaemia Nos

  • Hyper Igm
Lacrimal Apparatus Disease

  • Lacrimal Apparatus Diseases
Monoclonal Gammopathy Of Uncertain Significance

  • Monoclonal Gammopathy Of Undetermined Significance

  • Mgus

  • Mgus - [Monoclonal Gammopathy Of Undetermined Significance]

  • Monoclonal Gammopathy Nos

  • Iga Gammopathy

  • Monoclonal Gammoglobulinopathy
Lymphoma, Hodgkin, Classic

  • Hodgkin Lymphoma

  • Hodgkin Disease

  • Hodgkin'S Lymphoma

  • Hodgkins Lymphoma

  • Classic Hodgkin Lymphoma

  • CHL

  • Hodgkin Lymphoma, Susceptibility To

  • Hl

  • Hodgkin'S Sarcoma

  • Stage I Subdiaphragmatic Hodgkin Lymphoma

  • Stage Ii Subdiaphragmatic Hodgkin Lymphoma

  • Lymphoma, Hodgkin'S

  • Classic Hodgkin Disease

  • Hodgkin'S Disease

  • Lymphoma, Hodgkin, Susceptibility To

  • Hodgkin'S Disease Of Intrapelvic Lymph Nodes

  • Hodgkin'S Disease Of Lymph Nodes Of Inguinal Region And/Or Lower Limb

  • Malignant Lymphogranuloma

  • Malignant Lymphogranulomatosis

  • Malignant Hodgkin Lymphoma

  • Classical Hodgkin Lymphoma, Type Not Specified
Lymphoma, Mucosa-Associated Lymphoid Type

  • Malt Lymphoma

  • Gastric Lymphoma, Primary

  • Lymphoma, Malt, Somatic

  • Mucosa-Associated Lymphoid Tissue Lymphoma

  • Extranodal Marginal Zone B-Cell Lymphoma

  • MALTOMA

  • Marginal Zone B-Cell Lymphoma

  • Mucosa-Associated Lymphatic Tissue Lymphoma

  • Primary Gastric Lymphoma

  • Gastric Lymphoma

  • Familial Primary Gastric Lymphoma
Myeloma, Multiple

  • Multiple Myeloma

  • Plasma Cell Myeloma

  • Kahler Disease

  • Myelomatosis

  • Medullary Plasmacytoma

  • Multiple Myeloma, Resistance To

  • Myeloma

  • Plasma Cell Dyscrasia

  • Kahler'S Disease

  • Multiple Myeloma, Susceptibility To

  • Myeloma - Multiple

  • Kahler-Bozzolo Disease

  • Plasma Cell Myelomas

  • MM

  • Plasma Cell Neoplasm

  • Primary Systemic Amyloidosis

  • Primary Amyloidosis

  • Immunoglobulin Deposition Disease

  • Plasmacytic Myeloma

  • Multiple Myelomata

  • Multiple Myeloma Nos

  • Multiple Myeloma Without Mention Of Remission

  • Monostotic Plasma Cell Myeloma

  • Mm - [Multiple Myeloma]
Granulomatosis With Polyangiitis

  • GPA

  • Wegener Granulomatosis

  • Wegener Granulomatosis, Formerly

  • Midline Granulomatosis

  • Wg, Formerly

  • Necrotizing Respiratory Granulomatosis

  • Wg

  • Wegeners Granulomatosis

  • Pauci-Immune Glomerulonephritis Associated With Granulomatosis With Polyangiitis
Optic Nerve Disease

  • Optic Neuropathy

  • Disorder Of The Second Nerve

  • Optic Nerve Disorder

  • Optic Nerve

  • Abnormality Of The Optic Nerve

  • Optic Nerve Disorders

  • Neuropathy, Optic

  • Disorder Of The Optic Nerve
Behcet Syndrome

  • Behcet Disease

  • Behcet'S Syndrome

  • Behcet'S Disease

  • Behçet Disease

  • Bd

  • Adamantiades-Behcet Disease

  • Triple Symptom Complex

  • Behçet'S Disease

  • Behet'S Syndrome

  • Bd Syndrome

  • Behçet Syndrome

  • Behçet'S Syndrome

  • Behcet Triple Symptom Complex

  • Malignant Aphthosis

  • Old Silk Route Disease

  • Adamantiades-Behçet Disease
Mantle Cell Lymphoma

  • Lymphoma, Mantle Cell

  • Lcm

  • Mcl

  • Mantle Zone Lymphoma

  • Lymphoma Mantle-Cell

  • Lymphoma, Mantle-Cell

  • Malignant Lymphoma, Lymphocytic, Intermediate Differentiation, Diffuse

  • Malignant Lymphoma - Lymphocytic, Intermediate Differentiation

  • Diffuse Small Cleaved-Cell Lymphoma

  • Diffuse Small Cleaved Cell Malignant Lymphoma

  • Small Cleaved Cell Non-Hodgkin Lymphoma

  • Diffuse Non-Hodgkin Small Cleaved Cell Lymphoma

  • Malignant Lymphomatous Polyposis

  • Malignant Small Cell, Noncleaved, Diffuse Lymphoma

  • Malignant Undifferentiated Cell, Non-Burkitt Lymphoma

  • Cleaved Cell Lymphoma

  • Small Cell Mantle Cell Lymphoma

  • Small Cleaved Cell Malignant Lymphoma
Celiac Disease 1

  • Celiac Disease

  • Coeliac Disease

  • Celiac Sprue

  • Celiac Disease, Susceptibility To

  • Gluten-Sensitive Enteropathy

  • Nontropical Sprue

  • Sprue

  • CELIAC1

  • Celiac Disease, Susceptibility To, 1

  • Celiac Sprue 1

  • Celiac Sprue, Susceptibility To, 1

  • Gluten-Sensitive Enteropathy 1

  • Gluten-Sensitive Enteropathy, Susceptibility To, 1

  • Idiopathic Steatorrhea

  • Cœliac Disease

  • Gluten Intolerance

  • Gluten-Induced Enteropathy

  • Gluten Enteropathy

  • Celiac Disease, Susceptibility To, Type 1

  • Childhood Celiac Disease

  • Coeliac Rickets

  • Gee Disease

  • Gee-Herter Disease

  • Heubner-Herter Disease

  • Idiopathic Steatorrhoea

  • Thaysen'S Disease

  • Herter Gee Syndrome
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS14824 TNFSF13B Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17086 Tnfsf13b Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23530 Tnfsf13b Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
Inhibitory Antibodies (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P992101 Aritinercept Inhibitor 99.9% Unkown
HY-P992479 UBP1213 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris TNFSF13B VGNC VGNC:49662
Rattus norvegicus TNFSF13B RGD RGD:1561519
Macaca mulatta TNFSF13B VGNC VGNC:78594
Mus musculus TNFSF13B MGD MGI:1344376
Bos taurus TNFSF13B VGNC VGNC:107257
Felis catus TNFSF13B VGNC VGNC:66413
Others TNFSF13B NCBI